Longevity

Tesamorelin has the strongest regulatory file of any peptide in this space. The question is whether that approval proves what the longevity market thinks it proves.

Sermorelin's regulatory history is real. But the safety narrative built on top of it rests on a commercial withdrawal and a single cognition trial that may not have tested sermorelin at all.

Thymosin Alpha-1 is a real, internationally approved drug for a documented immune deficit, not a peptide-store rumour. Whether that same signal holds for a healthy 50-year-old with no diagnosis is the part nobody has actually tested.

GHK-Cu drops sharply with age and does striking things to cells in a dish. Whether any of that survives contact with actual human skin is a separate, unresolved question.

GHK-Cu has a plausible, multi-pathway mechanism for hair-follicle regeneration, but almost all the evidence is in vitro and animal-model work from the 1990s and 2000s. No human trial has tested it in hair, and the sole human RCT in skin found no effect.

CJC-1295, ipamorelin, sermorelin, and tesamorelin share one job — getting your own pituitary to release more growth hormone, the repair-and-recovery signal that fades after your twenties. Here is the appeal, the two peptide families inside the class, and how far the human proof actually goes.

MOTS-c and Epitalon are two very different longevity bets — one on your metabolism, one on the clock inside your cells. Here is what each could do for you, which angle fits your goal, and how far the human proof goes on both.

Your mitochondria don't just make energy — they send hormone-like signals that tell the body how to run, and the supply fades with age. Mitochondrial-derived peptides are that family. Here's what the class could do, how far proof goes, and where its most-studied member sits in July's FDA review.

BPC-157 and GHK-Cu both get sold as tissue-repair peptides, but they are tools for two different jobs — BPC-157 for deep tissue like tendon and gut, GHK-Cu for skin and surface. Here is what each could do for you, which goal each one fits, and how far the proof actually goes.

Sermorelin and tesamorelin both nudge your pituitary to make more growth hormone. One targets deep visceral fat with a real Phase 3 behind it; the other is the gentler GH-axis nudge with an FDA past. Here's which one fits which goal — and why one is still an approved drug and the other isn't.

CJC-1295 and ipamorelin are the internet's favourite growth-hormone pairing — but they do two different jobs. One raises your GH baseline for days from a single shot; the other fires a clean nightly pulse. Here's what each could do for you, which fits which goal, and why so many people run both.

Selank is Russia's attempt at an anxiety peptide that takes the edge off without the sedation, the fog, or the dependence a benzodiazepine leaves you with. The early promise is real and genuinely interesting — here's what it could do for you, and how far the human proof actually goes.

Ipamorelin asks your own body to release a clean pulse of growth hormone — the recovery, sleep and body-composition signal — without the stress-hormone mess older compounds caused. Here's what that could mean for you, and how far the human proof actually goes.

CJC-1295 is engineered to make your own pituitary release growth hormone for days from a single shot — and unusually, a real human trial says it works. Here's what that could mean for recovery, sleep and body composition, how far the proof goes, and why one name hides two different compounds.

Sermorelin is the growth-hormone peptide with a real FDA past — and a clever way of working: it nudges your own gland to make more GH instead of overriding it. Here's what it could do for you, how far the human proof actually goes, and why its availability isn't waiting on the July FDA vote.

MOTS-c is a tiny peptide your mitochondria release when you train — a signal that tells your body to handle fuel and hold onto strength like a younger one. The early science is genuinely exciting. Here is what it could do for you, and how far the human proof actually goes.

Selank and Semax get sold side by side as brain peptides, but they solve opposite problems — one calms, one sharpens. Here's what each could do for you, how far the Russian evidence actually goes, and why the July 2026 FDA review splits them apart.

Epithalon is the shortest peptide on the longevity menu, built on one bold idea — switching telomerase back on to rebuild the caps on your chromosomes. Here is what it could do for you, how far the proof actually goes, and where it sits on the July 2026 PCAC docket.

You've probably met ipamorelin as the second half of CJC-1295 and ipamorelin. On its own it's the quieter half — a small peptide built to ask your own body for a clean pulse of growth hormone. Here's what it could mean for you, why it earned the clean name, and how far the human proof goes.

MOTS-c is a tiny peptide your mitochondria make to help the body handle fuel and hold onto strength — and the level falls with age. Here's the plain-English tour: what it is, what the early science says it might do, and where the July 2026 FDA review just put it.